FGF basic/bFGF, Bovine
CAT:
804-HY-P7179-03
Size:
2 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
FGF basic/bFGF, Bovine
- UNSPSC Description: FGF-2 is a member of the fibroblast family involved in bone healing, cartilage repair, bone repair, and nerve regeneration. FGF-2 is also a mitotic promoter that accelerates cell proliferation. FGF-2 regulates immune processes by specifically targeting tyrosine kinase receptors and activating the FGF/FGFR signaling pathway. For example, FGF-2 is involved in the JAK-STAT signaling pathway to regulate cartilage metabolism and also activates ERK signaling to promote cartilage regeneration. FGF-2 combined with FGFR1/3 promoted degeneration and repair of articular cartilage, respectively[1]. FGF-2 is also a known carcinogen in GBM, which contributes to glioma growth and vascularization[2].FGF basic/bFGF protein, Bovine, consists of 146 amino acids, produced by E.coli with tag free.
- Type: Recombinant Proteins
- Assay Protocol: https://www.medchemexpress.com/cytokines/fgf-basic-bfgf-protein-bovine.html
- Purity: 98.0
- Smiles: PALPEDGGSG AFPPGHFKDP KRLYCKNGGF FLRIHPDGRV DGVREKSDPH IKLQLQAEER GVVSIKGVCA NRYLAMKEDG RLLASKCVTD ECFFFERLES NNYNTYRSRK YSSWYVALKR TGQYKLGPKT GPGQKAILFL PMSAKS
- Molecular Weight: Approximately 16.5 kDa
- References & Citations: [1]Wang X, et al. Analysis of segregation distortion and association of the bovine FGF2 with fertilization rate and early embryonic survival. Anim Genet. 2009 Oct;40(5):722-8.|[2]Zhang J, et al. FGF2: a key regulator augmenting tendon-to-bone healing and cartilage repair. Regen Med. 2020 Sep;15(9):2129-2142.|[3]Jimenez-Pascual A, et al. FGF2: a novel druggable target for glioblastoma? Expert Opin Ther Targets. 2020 Apr;24(4):311-318.
- Shipping Conditions: Blue Ice
- Storage Conditions: Stored at -20°C for 2 years