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8-OH-DPAT (hydrobromide)

CAT: 0804-HY-15688-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-15688-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
8-OH-DPAT (8-Hydroxy-DPAT) hydrobromide is a potent and selective 5-HT1A agonist with a pIC50 of 8.19. 8-OH-DPAT hydrobromide has selectivity of almost 1000 fold for a subtype of the 5-HT1 binding site[1].
CAS Number
76135-31-4
Product Name Alternative
8-Hydroxy-DPAT (hydrobromide)
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/8-oh-dpat-hydrobromide.html
Concentration
10mM
Purity
99.88
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
OC1=C2CC(N(CCC)CCC)CCC2=CC=C1.[H]Br
Molecular Formula
C16H26BrNO
Molecular Weight
328.29
Precautions
H315, H319, H335
References & Citations
1
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT1 Receptor; mLAG-3
Citation 01
Eur J Pharmacol. 2023 Dec 5:960:176147.|Acta Pharmacol Sin. 2025 Oct 9.|J Ethnopharmacol. 2026 Feb 28:357:120876.|Mol Neurobiol. 2025 Nov 24;63 (1) :163.|Nature. 2024 Jun;630 (8015) :237-246.|Neurochem Int. 2025 Jan 28:105937.|SSRN. 2025 Jun 19.

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