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BMAP 28 (bovine)

CAT: 0804-HY-P10402Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P10402Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BMAP 28, bovine is an antibacterial peptide. BMAP 28, bovine exhibits antimicrobial activity against gram-positive and gram-negative bacteria, by increasing cell membrane permeability, and causing leakage of cell contents. BMAP 28, bovine exhibits cytotoxicity to cancer cells and activated human lymphocytes. BMAP 28, bovine induces apoptosis through depolarization of mitochondrial membrane potential[1][2][3].
CAS Number
939963-76-5
UNSPSC
12352209
Target
Bacterial
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/bmap-28-bovine.html
Smiles
C([C@@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=C(O)C=C1)C(NCC(=O)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(O)=O)=O)[C@H](CC)C)=O)CCCNC(=N)N)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)CCC3)C(C)C)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)CCC2)=O)=O)CCCCN)=O)CCCCN)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC(CN)=O)=O)CC(C)C)=O)CCCNC(=N)N)=O)CO)=O)CC(C)C)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)[C@H](CC)C)=O)CC(C)C)=O)CCCNC(=N)N)=O)C)=O)C=4C=5C(NC4)=CC=CC5
Molecular Formula
C147H252N44O31
Molecular Weight
3131.85
References & Citations
[1]Brogden KA, et al., Antimicrobial peptides in animals and their role in host defences. Int J Antimicrob Agents. 2003 Nov;22 (5) :465-78. |[2]Guo Y, et al., A bovine myeloid antimicrobial peptide (BMAP-28) and its analogs kill pan-drug-resistant Acinetobacter baumannii by interacting with outer membrane protein A (OmpA) . Medicine (Baltimore) . 2018 Oct;97 (42) :e12832. |[3]Risso A, et al., BMAP-28, an antibiotic peptide of innate immunity, induces cell death through opening of the mitochondrial permeability transition pore. Mol Cell Biol. 2002 Mar;22 (6) :1926-35.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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