COX-2-IN-2

COX-2-IN-2

• CAS Number: 134729-13-8
• UNSPSC Description: COX-2-IN-2 is a selective and inducible COX2 inhibitor with an IC50 of 0.24 μM. COX-2-IN-1 is an anti-inflammatory compound with anti-inflammatory and analgesic activities.
• Target Antigen: COX
• Type: Reference compound
• Related Pathways: Immunology/Inflammation
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/1-_4-fluorophenyl_-5-[4-_methylsulfonyl_phenyl]-pyrazole-3-carbonitrile.html
• Purity: 99.53
• Solubility: DMSO : 50 mg/mL (ultrasonic)
• Smiles: N#CC1=NN(C2=CC=C(F)C=C2)C(C3=CC=C(S(=O)(C)=O)C=C3)=C1
• Molecular Weight: 341.36
• References & Citations: [1]Tsuji K, et al. Studies on anti-inflammatory agents. IV. Synthesis and pharmacological properties of 1,5-diarylpyrazoles and related derivatives. Chem Pharm Bull (1997), 45(6), 987-995.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C, 3 years (Powder)
• Clinical Information: No Development Reported