DuP-532
CAT:
804-HY-19094
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
DuP-532
- CAS Number: 124750-95-4
- UNSPSC Description: DuP-532 is an angiotensin type 1 receptor antagonist with potential activity in the suppression of hypertension and heart failure. DuP-532 can react with a range of aryl and heteroaryl halides to form perfluoroalkyl(hetero)arenes in moderate to high yields. Computational studies of DuP-532 suggest that coordination of a second phenyl ring ligand may lower the energy barrier for decarboxylation of perfluorocarboxylates, thereby promoting the perfluoroalkylation reaction[1].
- Target Antigen: Angiotensin Receptor
- Type: Reference compound
- Related Pathways: GPCR/G Protein
- Applications: Neuroscience-Neuromodulation
- Field of Research: Cardiovascular Disease
- Assay Protocol: https://www.medchemexpress.com/dup-532.html
- Smiles: O=C(C1=C(C(F)(C(F)(F)F)F)N=C(CCC)N1CC2=CC=C(C3=C(C4=NN=NN4)C=CC=C3)C=C2)O
- Molecular Weight: 506.43
- References & Citations: [1]A class of effective decarboxylative perfluoroalkylating reagents: [(phen)2Cu](O2CRF)
- Shipping Conditions: Room temperature
- Clinical Information: Phase 1