DuP 714

DuP 714

• CAS Number: 130982-43-3
• UNSPSC Description: DuP 714 is an oral active thrombin inhibitor with the IC50 values of 150 nM aganist thrombin-induced aggregation in washed human platelets. DuP 714 can be used for study of arterial thrombosi[1][2].
• Target Antigen: Thrombin
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/dup-714.html
• Smiles: CC(N[C@H](CC1=CC=CC=C1)C(N2[C@@H](CCC2)C(N[C@H](B(O)O)CCCNC(N)=N)=O)=O)=O
• Molecular Weight: 460.33
• References & Citations: [1]Reilly TM, et al. Effect of thrombin inhibitors on platelet functions: comparative analysis of DuP 714 and hirudin. Blood Coagul Fibrinolysis. 1992;3(5):513-517. |[2]Mitchell TJ, et al. Analysis of the thrombin inhibitor DuP 714 by an enzyme-linked immunosorbent assay. Blood Coagul Fibrinolysis. 1994;5(4):517-521.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported