Menthone

CAT: 0804-HY-N2381-01Size: 25 gDry Ice: NoHazardous: No
CAT#:0804-HY-N2381-01Size:25 g
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Description
Menthone, an orally active monoterpene that can be isolated from plants and Mentha oil with antibacterial, antitumor, antioxidation, and antivirus properties. Menthone is a main volatile component of the essential oil, and has anti-Inflammatory properties in Schistosoma mansoni infection and rheumatoid arthritis[1][2].
CAS Number
[10458-14-7]
UNSPSC
12352211
Hazard Statement
H302, H319, H334, H412
Target
NF-κB; Parasite
Type
Natural Products
Related Pathways
Anti-infection; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection; Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/menthone.html
Concentration
10mM
Purity
99.96
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C(C(C)C)CCC(C)C1
Molecular Formula
C10H18O
Molecular Weight
154.25
Precautions
H302, H319, H334, H412
References & Citations
[1]Mauricio G Zaia, et al. Anti-Inflammatory Properties of Menthol and Menthone in Schistosoma mansoni Infection. Front Pharmacol. 2016 Jun 17;7:170.|[2]Chen X, et al. A Natural Plant Ingredient, Menthone, Regulates T Cell Subtypes and Lowers Pro-inflammatory Cytokines of Rheumatoid Arthritis. J Nat Prod. 2022 Apr 22;85 (4) :1109-1117. |[3]Su YH, et al. Menthone supplementation protects from allergic inflammation in the lungs of asthmatic mice. Eur J Pharmacol. 2022 Sep 15;931:175222.|[4]Chen X, et al. Menthone inhibits type-I interferon signaling by promoting Tyk2 ubiquitination to relieve local inflammation of rheumatoid arthritis. Int Immunopharmacol. 2022 Nov;112:109228.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Schistosome

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