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VX-803 (M4344)

CAT: 1568-C14380-25mgSize: 25 mgDry Ice: NoHazardous: No
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CAT#:1568-C14380-25mgSize:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1613191-99-3
Synonyms
ATR inhibitor 2
Target
ATM/ATR
Applications
PI3K/Akt/mTOR
Smiles
C1CN (CCC1C (=O) N2CCN (CC2) C3COC3) C4=C (C=NC=C4NC (=O) C5=C6N=CC (=CN6N=C5N) F) F
Molecular Formula
C25H29F2N9O3
Additionnal Information
VX-803 (M4344, ATR inhibitor 2) is an ATP-competitive, orally active, and selective inhibitor of ataxia telangiectasia and Rad3 related (ATR) kinase with Ki of < 150 pM. VX-803 (M4344) potently inhibits ATR-driven phosphorylated checkpoint kinase-1 (P-Chk1) phosphorylation with IC50 of 8 nM. VX-803 (M4344) exhibits potential antineoplastic activity.
Storage Conditions
3 years -20°C powder

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