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VX-803 (M4344)

CAT: 0957-S9639-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-S9639-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
VX-803 (M4344, ATR inhibitor 2) is an ATP-competitive, orally active, and selective inhibitor of ataxia telangiectasia and Rad3 related (ATR) kinase with Ki of < 150 pM. VX-803 (M4344) potently inhibits ATR-driven phosphorylated checkpoint kinase-1 (P-Chk1) phosphorylation with IC50 of 8 nM. VX-803 (M4344) exhibits potential antineoplastic activity.
CAS Number
1613191-99-3
Synonyms
ATR inhibitor 2
Target
ATM/ATR
Activity
PI3K/Akt/mTOR
Molecular Formula
C25H29F2N9O3
Storage Conditions
3 years -20°C powder

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