VX-11e

• CAS Number :

  896720-20-0

• Synonyms :

  VTX-11e, Vertex-11e

• SKU :

  C12888-5mg

• Target :

  ERK

• Applications :

  MAPK

• Smiles :

  CC1=CN=C (N=C1C2=CNC (=C2) C (=O) NC (CO) C3=CC (=CC=C3) Cl) NC4=C (C=C (C=C4) F) Cl

• Molecular Formula :

  C24H20Cl2FN5O2

• Additionnal Information :

  VX-11e (VTX-11e, Vertex-11e) is a potent, selective, and orally bioavailable ERK inhibitor with IC50 of 17 nM (ERK1) and 15 nM (ERK2), over 200-fold selective over other kinases tested.

• Storage Conditions :

  2 years -80 in solvent