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GSK J4 HCl

CAT: 1568-C12418-10mM/1mLSize: 10 mm/ 1 mLDry Ice: YesHazardous: No
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CAT#:1568-C12418-10mM/1mLSize:10 mm/ 1 mL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1797983-09-5
Target
Histone Demethylase
Applications
Epigenetics
Smiles
CCOC (=O) CCNC1=CC (=NC (=N1) C2=CC=CC=N2) N3CCC4=CC=CC=C4CC3.Cl
Molecular Formula
C24H27N5O2.HCl
Additionnal Information
GSK J4 HCl is a cell permeable prodrug of GSK J1, which is the first selective inhibitor of the H3K27 histone demethylase JMJD3 and UTX with IC50 of 60 nM in a cell-free assay and inactive against a panel of demethylases of the JMJ family.
Storage Conditions
2 years -80 in solvent

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