GSK-J4

• CAS Number :

  1373423-53-0

• SKU :

  C03353-5mg

• Target :

  Histone Demethylase

• Applications :

  Epigenetics

• Additionnal Information :

  GSK-J4 is a potent dual inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A that ameliorates experimental autoimmune encephalomyelitis (EAE) . It is also an inhibitor of TNF-α production, with an IC50 of 9 μM. It shows potential as a treatment for inflammatory and autoimmune disorders.