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GSK J1

CAT: 1568-C12794-01Size: 10 mgDry Ice: YesHazardous: No
C12794-0110 mg
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1373422-53-7
SKU
C12794-10mg
Target
Histone Demethylase
Applications
Epigenetics
Smiles
C1CN (CCC2=CC=CC=C21) C3=NC (=NC (=C3) NCCC (=O) O) C4=CC=CC=N4
Molecular Formula
C22H23N5O2
Additionnal Information
GSK-J1 is a highly potent inhibitor of H3K27 histone demethylase JMJD3 (KDM6B) and UTX (KDM6A) with IC50 of 60 nM in cell-free assays for JMJD3 (KDM6B), respectively, >10-fold selectivity over other tested demethylases, with IC50 of 0.95μM and 1.76μM towards JARID1B/C.
Storage Conditions
2 years -80 in solvent

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