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Illudin S

CAT: 1568-C04134-1mgSize: 1 mgDry Ice: NoHazardous: No
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CAT#:1568-C04134-1mgSize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1149-99-1
Target
DNA/RNA Synthesis
Applications
Cell Cycle
Molecular Formula
C15H20O4
Additionnal Information
Illudin S is a potent antitumor sesquiterpene metabolically activated into reactive intermediates that cause a complete block of cell cycling at the G1-S phase interface, particularly in myeloid and T-lymphocyte leukemia cells (IC50 = 6-11 nM) . It was first isolated from the fungus Clitocybe illudens and disrupts thymidine-dependent DNA synthesis without affecting RNA or protein synthesis.

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