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Illudin M

CAT: 0804-HY-122493-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-122493-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Illudin M is a cytotoxic fungal sesquiterpene that can be isolated from the culture medium of Omphalotus illudens mushrooms. Illudin M can alkylate DNA. Illudin M has anti-tumor activities[1][2].
CAS Number
1146-04-9
UNSPSC
12352211
Target
Apoptosis; DNA Alkylator/Crosslinker
Type
Natural Products
Related Pathways
Apoptosis; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/illudin-m.html
Purity
99.53
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C2=CC(C)([C@@H](C2=C(C3([C@@]1(C)O)CC3)C)O)C
Molecular Formula
C15H20O3
Molecular Weight
248.32
References & Citations
[1]Rainer Schobert, et al. Conjugates of the fungal cytotoxin illudin M with improved tumour specificity. Bioorg Med Chem. 2008 Sep 15;16 (18) :8592-7.|[2]Dr. Philipp Le, et al. A Chemical Proteomic Analysis of Illudin‐Interacting Proteins. Chemistry. 2019 Sep 25; 25 (54) : 12644–12651.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported