CHZ868

CAT: 0926-VAD89538-02Size: 2 mgDry Ice: NoHazardous: No

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CAT#:0926-VAD89538-02Size:2 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1895895-38-1

MDL Number

MFCD30533612

Smiles

CC1=C (C=CC2=C1N=C (N2C) NC3=C (C=C (C=C3) F) F) OC4=CC (=NC=C4) NC (=O) C

Molecular Formula

C22H19F2N5O2

Molecular Weight

423.42 g/mol

Controlled

Chemical Information

Chz868

CHZ868 is a memger of the class of benzimidazoles that is benzimidazole that is substituted by methyl groups at positions 1 and 4, by a 2,4-difluoroanilino group at position 2, and by a (2-acetamidopyridin-4-yl)oxy group at position 5. It is a type II JAK2 inhibitor with antineoplastic activity. It has a role as an antineoplastic agent and an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. It is a member of acetamides, a member of benzimidazoles, a member of pyridines, an aromatic amine, an aromatic ether, a difluorobenzene and a secondary amino compound.

CAS Number	1895895-38-1
PubChem CID	91885989
IUPAC Name	N-[4-[2-(2,4-difluoroanilino)-1,4-dimethylbenzimidazol-5-yl]oxy-2-pyridinyl]acetamide
Molecular Formula	C22H19F2N5O2
Molecular Weight	423.4
XLogP	3.8
Topological Polar Surface Area	81.1
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	5
Heavy Atom Count	31
Formal Charge	0
Complexity	629

SMILES

CC1=C(C=CC2=C1N=C(N2C)NC3=C(C=C(C=C3)F)F)OC4=CC(=NC=C4)NC(=O)C

InChI

InChI=1S/C22H19F2N5O2/c1-12-19(31-15-8-9-25-20(11-15)26-13(2)30)7-6-18-21(12)28-22(29(18)3)27-17-5-4-14(23)10-16(17)24/h4-11H,1-3H3,(H,27,28)(H,25,26,30)

InChIKey

KQQLBXFPTDVFAJ-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 1895895-38-1

CID: 91885989

Formula: C22H19F2N5O2

MW: 423.4

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	423.4
XLogP3	3.8
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	5
Exact Mass	423.15068119
Monoisotopic Mass	423.15068119
Topological Polar Surface Area	81.1 Å²
Heavy Atom Count	31
Formal Charge	0
Complexity	629
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Alternative Products

Catalog	Name
S7899-100mg	CHZ868
A15937-50	CHZ868 50mg
A15937-100	CHZ868 100mg
A15937-25	CHZ868 25mg
A15937-10	CHZ868 10mg
A15937-5	CHZ868 5mg
A15937-2	CHZ868 2mg

CHZ868

Chemical Information

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