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CHZ868

CAT: 0026-B2475-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-B2475-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CHZ868 is a potent and selective type II JAK2 inhibitor (IC₅₀ = 110 nM). JAK2 and MPL mutant cell lines are sensitive to CHZ868, including type I JAK inhibitor persistent cells. CHZ868 displays significant activity in murine MPN models and induces reductions in mutant allele burden not observed with type I JAK inhibitors.
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months

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