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CHZ868

CAT: 0957-S7899-100mgSize: 100 mgDry Ice: NoHazardous: No
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CAT#:0957-S7899-100mgSize:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1895895-38-1
Target
JAK
Applications
Angiogenesis
Molecular Formula
C22H19F2N5O2
Additionnal Information
CHZ868 is an inhibitor of type II JAK2 with an IC50 value of 0.17 μM in EPOR JAK2 WT Ba/F3 cells. CHZ868 demonstrates 60- to 70-fold higher inhibition of JAK1-/TYK2-mediated nuclear STAT1 translocation compared to pan-JAK inhibitors.

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