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Thalidomide-NH-PEG2-C2-CH2

CAT: 0804-HY-158343Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-158343Size:1 Each
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Description
Thalidomide-NH-PEG2-C2-CH2 is a conjugate of E3 ligase ligand and linker. Thalidomide-NH-PEG2-C2-CH2 is utilized for synthesis of PROTAC TEAD degrader-1.
CAS Number
2064175-30-8
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/thalidomide-nh-peg2-c2-ch2.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C2C=CC(NCCOCCOCCN)=C1)N(C(CC3)C(NC3=O)=O)C2=O
Molecular Formula
C19H24N4O6
Molecular Weight
404.42
References & Citations
[1]Li H, et al., Design, Synthesis, and Bioevaluation of Transcriptional Enhanced Assocciated Domain (TEAD) PROTAC Degraders. ACS Med Chem Lett. 2024 Apr 22;15 (5) :631-639.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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