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HME2 rabbit pAb

CAT: 0855-ES15697-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES15697-01Size:50 µL
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Background
Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. [provided by RefSeq, Jul 2008]
Description
Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. [provided by RefSeq, Jul 2008],
UniProt
P19622
Swiss Prot
P19622
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human HME2 AA range: 225-275
Target
HME2
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Nucleus.
Gene ID (Human)
2020

UniProtKB · P19622

Homeobox protein engrailed-2

HME2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P19622
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
EN2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Homeobox protein en-2, Hu-En-2
EC number
—
Processing
—
Secondary accessions
A4D252, Q549U3, Q9UD58
Protein keywords

Disease

AutismAutism spectrum disorder

Molecular function

Developmental proteinDNA-binding

Domain

Homeobox

Cellular component

Nucleus

Technical term

Proteomics identificationReference proteome

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