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KSI-3716

CAT: 0804-HY-12703-01Size: 10 mM - 1 mLDry Ice: NoHazardous: No
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CAT#:0804-HY-12703-01Size:10 mM - 1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KSI-3716 is a potent c-Myc inhibitor that blocks c-MYC/MAX binding to target gene promoters. KSI-3716 is an effective intravesical chemotherapy agent for bladder cancer[1].
CAS Number
1151813-61-4
UNSPSC
12352005
Target
Autophagy; c-Myc
Type
Reference compound
Related Pathways
Apoptosis; Autophagy
Applications
Neuroscience-Neurodegeneration
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/KSI-3716.html
Purity
98.94
Solubility
DMSO : 5 mg/mL (ultrasonic)
Smiles
ClC1=CC=C(Br)C(NC(NC2=CC=C(Cl)C=C2)=C3C(C)=O)=C1C3=O
Molecular Formula
C17H11BrCl2N2O2
Molecular Weight
426.09
References & Citations
[1]Jeong KC, et al. Intravesical instillation of c-MYC inhibitor KSI-3716 suppresses orthotopic bladder tumor growth. J Urol. 2014 Feb;191 (2) :510-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported