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ATC-324

CAT: 0957-E8305-1mgSize: 1 mgDry Ice: NoHazardous: No
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CAT#:0957-E8305-1mgSize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2925060-81-5
Target
Androgen Receptor
Applications
Endocrinology & Hormones
Additionnal Information
ATC-324 is a potent AUTOphagy-TArgeting Chimera (AUTOTAC) degrader of androgen receptor (AR) with a DC50 of 2.05 μM. It induces autophagy–lysosomal degradation of AR, reduces nuclear AR and AR-V7 activity, and causes cytotoxicity in AR-positive prostate cancer cells, making it useful for prostate cancer research.