Products for Research Use Only
RegisterLogin

ATC 0175

CAT: 0013-GTR19201430-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19201430-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
ATC 0175 hydrochloride is a potent, selective, and orally active MCH1 receptor antagonist with additional affinity for 5-HT2B and 5-HT1A receptors. It demonstrates antidepressant and anxiolytic effects in animal models, making it a useful research tool for studying depression and anxiety disorders in both in vitro and in vivo experimental systems.
CAS Number
510733-97-8
Product Name Alternative
MCH1-R, MCHR1 (GPR24), MCHR, MCHR2, Melanin-concentrating Hormone Receptor, MelaninconcentratingHormoneReceptor (MCHR), MelaninconcentratingHormoneReceptor, Melaninconcentrating Hormone Receptor (MCHR), ATC 0175 hydrochloride, ATC 0175 Hydrochloride, ATC0175 Hydrochloride, ATC-0175 Hydrochloride, 5HTReceptor, 5HT Receptor, 5-HT1A, 5-HT2B
Field of Research
Metabolism Research, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction
Purity
99.84% (May vary between batches)
Solubility
Ethanol:22.5 mg/mL (48.71 mM) ; DMSO:9 mg/mL (19.48 mM)
Smiles
N (C) (C) C=1C2=C (N=C (N[C@H]3CC[C@@H] (NC (=O) C4=CC (F) =C (F) C=C4) CC3) N1) C=CC=C2.Cl
Molecular Formula
C23H26ClF2N5O
Molecular Weight
461.93
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Atc-0175
CAS Number510733-97-8
PubChem CID9934032
IUPAC NameN-[4-[[4-(dimethylamino)quinazolin-2-yl]amino]cyclohexyl]-3,4-difluorobenzamide;hydrochloride
Molecular FormulaC23H26ClF2N5O
Molecular Weight461.9
Topological Polar Surface Area70.2
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count7
Rotatable Bond Count5
Heavy Atom Count32
Formal Charge0
Complexity601
SMILES
CN(C)C1=NC(=NC2=CC=CC=C21)NC3CCC(CC3)NC(=O)C4=CC(=C(C=C4)F)F.Cl
InChI
InChI=1S/C23H25F2N5O.ClH/c1-30(2)21-17-5-3-4-6-20(17)28-23(29-21)27-16-10-8-15(9-11-16)26-22(31)14-7-12-18(24)19(25)13-14;/h3-7,12-13,15-16H,8-11H2,1-2H3,(H,26,31)(H,27,28,29);1H
InChIKey
HUUPKFUYSQNNLO-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Atc-0175
CAS: 510733-97-8
CID: 9934032
Formula: C23H26ClF2N5O
MW: 461.9
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight461.9
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count7
Rotatable Bond Count5
Exact Mass461.1793945
Monoisotopic Mass461.1793945
Topological Polar Surface Area70.2 Ų
Heavy Atom Count32
Formal Charge0
Complexity601
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19170651-01Ro60-0175
GTR18886455-01HP-0175 protein
GTR19200922-01Ro 60-0175 fumarate
GTR19257868-01ATC-324
GTR19020997Recombinant Helicobacter pylori Putative peptidyl-prolyl cis-trans isomerase HP_0175 (HP-0175) (Active)
GTR19262027-01AT-0174
GTR19185359-01EB-0176
GTR19281005-01AND-017
GTR19257591-01Compound SA91-0178
GTR19200173-01JTC-017

Alternative Products

CatalogName
HY-123838-01Ro60-0175
HY-103140-01Ro60-0175 (fumarate)
T22591-01ATC 0175 hydrochloride
M12587-01Ro 60-0175
532566Ro 60-0175 fumarate

Popular Products