CRTh2 antagonist 2

• UNSPSC Description:

  CRTh2 antagonist 2 is selective and potent CRTH2 antagonist extracted from patent US20140148470A1, compound Example 1, has an IC50 of ≤10 nM. CRTh2 antagonist 2 can be used in research of androgenic alopecia[1].

• Target Antigen:

  Prostaglandin Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Field of Research:

  Endocrinology

• Assay Protocol:

  https://www.medchemexpress.com/crth2-antagonist-2.html

• Purity:

  99.78

• Solubility:

  DMSO : 125 mg/mL (ultrasonic)

• Smiles:

  O=C(O)CC1=C(N(C)C)N=C(CC2=CC=C(NC(C3=CC=C4C=CC=CC4=C3)=O)C=C2)N=C1Cl

• Molecular Weight:

  474.94

• References & Citations:

  [1]Andreas Schnapp, et al. Pyrimidine compounds for treating hairloss. US20140148470A1.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  780763-95-3