ROCK2-IN-8
CAT:
804-HY-116420-01
Size:
1 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
ROCK2-IN-8
- CAS Number: 681173-76-2
- UNSPSC Description: ROCK2-IN-8 (Compound 1) is an orally active ROCK2 inhibitor, with an IC50 of 7.2 nM. ROCK2-IN-8 can be used for the research of aqueous humor outflow in porcine eyes and myosin light chain phosphorylation[1].
- Target Antigen: ROCK
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage;Cytoskeleton;Stem Cell/Wnt;TGF-beta/Smad
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/rock2-in-8.html
- Purity: 99.38
- Solubility: DMSO : 5 mg/mL (ultrasonic)
- Smiles: O=C(C1OC2=C(OC1)C=CC=C2)NC3=NC(C4=CC=NC=C4)=CS3
- Molecular Weight: 339.37
- References & Citations: [1]Feng Y, et al. Discovery of substituted 4-(pyrazol-4-yl)-phenylbenzodioxane-2-carboxamides as potent and highly selective Rho kinase (ROCK-II) inhibitors. J Med Chem. 2008 Nov 13;51(21):6642-5.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C, 3 years (Powder)
- Clinical Information: No Development Reported