AZD8421

CAT: 1568-C01989-01Size: 5 mgDry Ice: NoHazardous: No

CAT#:1568-C01989-01Size:5 mg

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AVAILABILITY: InStock

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

3047321-53-6

SKU

C01989-5mg

Target

CDK

Applications

Cell Cycle

Additionnal Information

AZD8421 is a potent and highly selective inhibitor of Cyclin-dependent Kinase 2 (CDK2), with an IC50 against CDK2 of 9nM with selectivity over CDK1, CDK4 and CDK6. It also exhibits an anti-proliferative effect, effectively inhibits Rb phosphorylation, and shows strong activity both as a monotherapy and in combination with CDK4/6 inhibitors in breast and ovarian cancer models.

Related Products

Catalog	Name
C12391-01	AZD2461
C17883-01	AZD2461
C08346-01	Sapitinib (AZD8931)
C16689-01	Sapitinib (AZD8931)

Alternative Products

Catalog	Name
T201366-01	AZD8421
A24273-50	AZD8421 50mg
A24273-100	AZD8421 100mg
A24273-5	AZD8421 5mg
A24273-10	AZD8421 10mg

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