Sapitinib (AZD8931)

CAT: 1568-C08346-01Size: 5 mgDry Ice: YesHazardous: No
CAT#:1568-C08346-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
848942-61-0
SKU
C08346-50mg
Target
EGFR
Applications
Protein Tyrosine Kinase
Smiles
CNC (=O) CN1CCC (CC1) OC2=C (C=C3C (=C2) C (=NC=N3) NC4=C (C (=CC=C4) Cl) F) OC
Molecular Formula
C23H25ClFN5O3
Additionnal Information
Sapitinib (AZD8931) is a reversible, ATP competitive inhibitor of EGFR, ErbB2 and ErbB3 with IC50 of 4 nM, 3 nM and 4 nM in cell-free assays, more potent against NSCLC cell, 100-fold more selective for the ErbB family than MNK1 and Flt. Phase 2.
Storage Conditions
2 years -80 in solvent

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