AzGGK (TFA)

• UNSPSC Description:

  AzGGK TFA is an unnatural amino acid. AzGGK TFA is site-specifically incorporated into proteins via genetic-code expansion. AzGGK TFA can be used as a site-specific probe for ubiquitylation and SUMOylation. AzGGK TFA is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups[1].

• Target Antigen:

  Fluorescent Dye

• Type:

  Reference compound

• Related Pathways:

  Others

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/azggk-tfa.html

• Solubility:

  DMSO : 125 mg/mL (ultrasonic)

• Smiles:

  [N-]=[N+]=NCC(NCC(NCCCC[C@H](N)C(O)=O)=O)=O.OC(C(F)(F)F)=O

• Molecular Weight:

  400.31

• References & Citations:

  [1]Fottner M, et al. Site-specific ubiquitylation and SUMOylation using genetic-code expansion and sortase. Nat Chem Biol. 2019 Mar;15(3):276-284.

• Shipping Conditions:

  Blue Ice

• Clinical Information:

  No Development Reported