Camstatin (TFA)

• Description:

  Camstatin TFA, a functionally active 25-residue fragment of PEP-19's IQ motif, binds calmodulin and inhibits neuronal nitric oxide (NO) synthase[1].

• UNSPSC:

  12352209

• Target:

  NO Synthase

• Type:

  Peptides

• Related Pathways:

  Immunology/Inflammation

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/camstatin-tfa.html

• Solubility:

  H2O

• Smiles:

  O=C([C@@H](N)C)N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N)=O)CO)=O)=O)C)=O)CCCCN)=O)CCCCN)=O)CCCCN)=O)CCC(N)=O)=O)CC2=CC=CC=C2)=O)CCCCN)=O)CCCNC(N)=N)=O)CC3=CC=CC=C3)=O)CCC(N)=O)=O)C)=O)CCC(N)=O)=O)[C@H](CC)C)=O)C)=O)C(C)C)=O)C)=O)C)=O)CCCNC(N)=N)=O)CCC(O)=O)=O)[C@@H](C)O)=O)CCC(O)=O)=O)CCC1.OC(C(F)(F)F)=O

• Molecular Formula:

  C122H203N39O34.xC2HF3O2

• Molecular Weight:

  2760.16 (free base)

• References & Citations:

  [1]J Bradley Dickerson, et al. The influence of phosphorylation on the activity and structure of the neuronal IQ motif protein, PEP-19. Brain Res. 2006 May 30;1092 (1) :16-27.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported

• Isoform:

  NNOS