2',3'-Dideoxyadenosine

• Description:

  2',3'-Dideoxyadenosine is an inhibitor of HIV replication[1]. Antiretroviral activity[1]. Antiviral efficacy[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  HIV

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/2_acute_,3_acute_-Dideoxyadenosine.html

• Concentration:

  10mM

• Purity:

  99.96

• Solubility:

  DMSO : 125 mg/mL (ultrasonic)

• Smiles:

  OC[C@@H]1CC[C@H] (N2C (N=CN=C3N) =C3N=C2) O1

• Molecular Formula:

  C10H13N5O2

• Molecular Weight:

  235.25

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Balzarini J, et al. Conversion of 2',3'-dideoxyadenosine (ddA) and 2',3'-didehydro-2',3'-dideoxyadenosine (d4A) to their corresponding aryloxyphosphoramidate derivatives markedly potentiates their activity against human immunodeficiency virus and hepatitis B virus. FEBS Lett. 1997 Jun 30;410 (2-3) :324-8.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  HIV-1; HIV-2

• CAS Number:

  4097-22-7