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CHIKV-IN-5

CAT: 0804-HY-169429Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-169429Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CHIKV-IN-5 (Compound 26) is a CHIKV inhibitor (EC90 = 0.45 μM) . CHIKV-IN-5 inhibits CHIKV replication at a late stage in the virus life cycle by blocking structural protein translation. CHIKV-IN-5 has great in vitro mouse microsomal stability. CHIKV-IN-5 reduces footpad swelling and decreases virus dissemination to other tissues in mice infected with CHIKV[1].
CAS Number
2568903-91-1
UNSPSC
12352005
Target
Flavivirus
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/chikv-in-5.html
Smiles
O=C(NC1=NC(C2=CC(NC3=CC=C(C=C3)C#N)=CC=C2)=CS1)C4=C(N=CC=C4)SC
Molecular Formula
C23H17N5OS2
Molecular Weight
443.54
References & Citations
[1]Garzan, et al. 4-Substituted-2-Thiazole Amides as Viral Replication Inhibitors of Alphaviruses. Journal of medicinal chemistry. 2024, 67 (23), 20858–20878.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported