CHIKV-IN-3

• UNSPSC Description:

  CHIKV-IN-3 is a potent against two low-passage CHIKV inhibitor with EC50 values of 1.55 and 0.14 μM for CHIKV-122508 and CHIKV-6708, respectively. CHIKV-IN-3 acts on the host cells to interfere with the viral replication. CHIKV-IN-3 displays minimal cytotoxic liability (CC50>100 μM). Prophylactic effect[1].

• Target Antigen:

  DNA/RNA Synthesis

• Type:

  Peptides

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/chikv-in-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  [H][C@@]12CCC([C@@H]([C@]1(CCCC2(C)C)C)C/C=C3C(NC4=C/3C=CC=C4Cl)=O)=C

• Molecular Weight:

  383.95

• References & Citations:

  [1]Tran QTN, et al. Discovery and development of labdane-oxindole hybrids as small-molecule inhibitors against chikungunya virus infection. Eur J Med Chem. 2022; 230:114110.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported