CHIKV-IN-2
CAT:
804-HY-132174-06
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CHIKV-IN-2
- CAS Number: 2361289-44-1
- UNSPSC Description: CHIKV-IN-2 is a potent inhibitor against Chikungunya virus (CHIKV), with excellent cellular antiviral activity (EC90=270 nM) and improved liver microsomal stability. CHIKV-IN-2 shows inhibitory activity against a cellular target Dihydroorotate Dehydrogenase (DHODH), which interacts with various viruses and regulate their replication via depleting intracellular pyrimidine pools[1].
- Target Antigen: Dengue virus; Dihydroorotate Dehydrogenase; Flavivirus
- Type: Reference compound
- Related Pathways: Anti-infection;Metabolic Enzyme/Protease
- Field of Research: Infection
- Assay Protocol: https://www.medchemexpress.com/chikv-in-2.html
- Purity: 99.21
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=C(NC1=CC=C(C(C)(C)C#N)C=C1)C2=CC3=C(CCCCC3)C=C2OC
- Molecular Weight: 362.46
- References & Citations: [1]Ahmed SK, et, al. Targeting Chikungunya Virus Replication by Benzoannulene Inhibitors. J Med Chem. 2021 Apr 22;64(8):4762-4786.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C, 3 years (Powder)
- Clinical Information: No Development Reported