Products for Research Use Only
RegisterLogin

Triacsin C

CAT: 0804-HY-N6707-01Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N6707-01Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Triacsin C (WS 1228A), is an orally active and intracellular long-chain acyl-CoA synthetases (ACSL) inhibitor, which can be isolated from Streptomyces aureofaciens. Triacsin C inhibits TAG accumulation into lipid droplets (LD) by suppressing ACSL activity[1]. Triacsin C exhibits highly inhibitory effect against rotavirus replication[2].
CAS Number
76896-80-5
Product Name Alternative
WS 1228A; FR 900190
UNSPSC
12352211
Hazard Statement
H315, H319, H335
Target
Parasite
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/triacsin-c.html
Purity
99.08
Solubility
DMSO : 5 mg/mL (ultrasonic; warming)
Smiles
CCC/C=C/C/C=C/C=C/C=N/NN=O
Molecular Formula
C11H17N3O
Molecular Weight
207.27
Precautions
H315, H319, H335
References & Citations
[1]Dechandt CRP, et al. Triacsin C reduces lipid droplet formation and induces mitochondrial biogenesis in primary rat hepatocytes. J Bioenerg Biomembr. 2017 Oct;49 (5) :399-411.|[2]Kim Y, et al. Novel triacsin C analogs as potential antivirals against rotavirus infections. Eur J Med Chem. 2012 Apr;50:311-8.|[3]Guo F, et al. Amelioration of Cryptosporidium parvum infection in vitro and in vivo by targeting parasite fatty acyl-coenzyme A synthetases. J Infect Dis. 2014 Apr 15;209 (8) :1279-87. |[4]Matsuda D, et al. Anti-atherosclerotic activity of triacsin C, an acyl-CoA synthetase inhibitor. J Antibiot (Tokyo) . 2008 May;61 (5) :318-21.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

Related Products

CatalogName
HY-140336-01C-NH-Boc-C-Bis- (C-PEG1-Boc)
HY-138383CHO-C-PEG2-C-CHO
HY-B0896-01Triacetin
HY-126605-01Trinactin
HY-168132Thalidomide-NH-C-C6H10-C-acid
HY-161974Adamantan-C-amide-PEG2-C-Br
HY-W382140-014′-C-Fluoro-2′-C-methyluridine
HY-178831Azacyclohexane-C-piperazine-C (OCH3) 2
HY-161210Thalidomide-azetidine-C-PIP-C-boc
HY-N15713Lucidone C

Alternative Products

CatalogName
B7070-.5Triacsin C
A13999-2Triacsin C 2mg
sc-477680ATriacsin C, lyophilized
A13999-1Triacsin C 1mg
9683-500EZSolution™ Triacsin C
A13999-5Triacsin C 5mg
A13999-0.5Triacsin C 500ug
sc-200574Triacsin C Solution in DMSO
291031-01Triacsin C discontinued. See 256968
BIT1004-01Triacsin C from Streptomyces sp.

Popular Products