Alpha-Cyperone

CAT: 0804-HY-N0710-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N0710-01Size:1 mg
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Description
Alpha-Cyperone (α-Cyperone) is associated with the down-regulation of COX-2, IL-6, Nck-2, Cdc42 and Rac1, resulting in reduction of inflammation, which would be highly beneficial for treatment of inflammatory diseases such as AD.
CAS Number
[473-08-5]
Product Name Alternative
α-Cyperone; (+) -α-Cyperone
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/alpha-Cyperone.html
Purity
99.68
Solubility
DMSO : 100 mg/mL (ultrasonic) |Ethanol : 140 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic)
Smiles
O=C1C(C)=C2C[C@H](C(C)=C)CC[C@@]2(C)CC1
Molecular Formula
C15H22O
Molecular Weight
218.33
Precautions
H302, H315, H319, H335
References & Citations
[1]Jung, S. H. et al. alpha-Cyperone, isolated from the rhizomes of Cyperus rotundus, inhibits LPS-induced COX-2 expression and PGE2 production through the negative regulation of NFkappaB signalling in RAW 264.7 cells. Journal of ethnopharmacology 147, 208-214, doi:10.1016/j.jep.2013.02.034 (2013) .|[2]Azimi, A. et al. alpha-Cyperone of Cyperus rotundus is an effective candidate for reduction of inflammation by destabilization of microtubule fibers in brain. Journal of ethnopharmacology, doi:10.1016/j.jep.2016.06.058 (2016) .
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite

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