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Anticancer agent 194

CAT: 0804-HY-162311Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-162311Size:1 Each
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Description
Anticancer agent 194 (compound 10p) is a ferroptosis and autophagy inducer. Anticancer agent 194 arrests colon cancer cell cycle at G2/M phase, but can't induce cell apoptosis. Anticancer agent 194 independently triggeres cell ferroptosis and autophagy through the massive accumulation of ROS[1].
CAS Number
2767204-90-8
UNSPSC
12352005
Target
Autophagy; Ferroptosis; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Apoptosis; Autophagy; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-194.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCCl)N1C2=CC=C(OC)C=C2NCC1
Molecular Formula
C12H16ClN3O2
Molecular Weight
269.73
References & Citations
[1]Tingting Liang, et al. Discovery of novel urea derivatives as ferroptosis and autophagy inducer for human colon cancer treatment. Eur J Med Chem. 2024 Feb 24:268:116277.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported