Anticancer agent 194
CAT:
804-HY-162311
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Anticancer agent 194
- CAS Number: 9007-83-4
- UNSPSC Description: Anticancer agent 194 (compound 10p) is a ferroptosis and autophagy inducer. Anticancer agent 194 arrests colon cancer cell cycle at G2/M phase, but can't induce cell apoptosis. Anticancer agent 194 independently triggeres cell ferroptosis and autophagy through the massive accumulation of ROS[1].
- Target Antigen: Autophagy; Ferroptosis; Reactive Oxygen Species
- Type: Reference compound
- Related Pathways: Apoptosis;Autophagy;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/anticancer-agent-194.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(NCCCl)N1C2=CC=C(OC)C=C2NCC1
- Molecular Weight: 269.73
- References & Citations: [1]Tingting Liang, et al. Discovery of novel urea derivatives as ferroptosis and autophagy inducer for human colon cancer treatment. Eur J Med Chem. 2024 Feb 24:268:116277.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported