Coptisine (Sulfate)
CAT:
804-HY-N0430A-02
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Coptisine (Sulfate)
- CAS Number: 1198398-71-8
- UNSPSC Description: Coptisine Sulfate is an alkaloid from Chinese goldthread, and acts as an efficient uncompetitive IDO inhibitor with a Ki value of 5.8 μM and an IC50 value of 6.3 μM[1].
- Target Antigen: Indoleamine 2,3-Dioxygenase (IDO)
- Type: Natural Products
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Metabolism-protein/nucleotide metabolism
- Field of Research: Cancer; Metabolic Disease
- Assay Protocol: https://www.medchemexpress.com/coptisine-sulfate.html
- Purity: 99.37
- Solubility: DMSO : 1 mg/mL (ultrasonic;warming;heat to 60°C)
- Smiles: O=S(O)([O-])=O.C1(C(CC[N+]2=C1C=C(C=C3)C(C4=C3OCO4)=C2)=C5)=CC6=C5OCO6
- Molecular Weight: 417.39
- References & Citations: [1]Yu D, et al. The IDO inhibitor coptisine ameliorates cognitive impairment in a mouse model of Alzheimer's disease. J Alzheimers Dis. 2015;43(1):291-302.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, sealed storage, away from moisture and light)
- Clinical Information: No Development Reported