MAC-545496
CAT:
804-HY-130613-04
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
MAC-545496
- CAS Number: 838810-96-1
- UNSPSC Description: MAC-545496 is a nanomolar inhibitor of glycopeptide-resistance-associated protein R (GraR). MAC-545496 displays strong binding affinity to the full-length GraR protein (Kd ≤ 0.1 nM). MAC-545496 is an antivirulence agent that reverses β-lactam resistance in Methicillin-resistant strains (MRSA)[1].
- Target Antigen: Bacterial
- Type: Reference compound
- Related Pathways: Anti-infection
- Field of Research: Infection
- Assay Protocol: https://www.medchemexpress.com/mac-545496.html
- Purity: 98.01
- Solubility: DMSO : 250 mg/mL (ultrasonic)
- Smiles: O=C(NC(NC1=NC=C(Cl)C=C1)=S)C2=CC=C(N3CCCCC3)C([N+]([O-])=O)=C2
- Molecular Weight: 419.89
- References & Citations: [1]El-Halfawy OM, et al. Discovery of an antivirulence compound that reverses β-lactam resistance in MRSA. Nat Chem Biol. 2019 Nov 25.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported