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CLB-016

CAT: 0804-HY-113662Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-113662Size:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CLB-016 is a potent Hypoxia-inducible factor (HIF-1) inhibitor with an IC50 of 19.1 μM. CLB-016 significantly suppresses HIF-1-mediated hypoxia response[1].
CAS Number
[1005636-29-2]
UNSPSC
12352005
Target
HIF/HIF Prolyl-Hydroxylase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/clb-016.html
Smiles
O=C(C1=NN(CC)C=C1NC(C2=CC=C(CN3N=C(C)C=C3C)O2)=O)N
Molecular Formula
C17H20N6O3
Molecular Weight
356.38
References & Citations
[1]Yasuda Y, et al. Design, synthesis, and structure-activity relationships of 1-ethylpyrazole-3-carboxamide compounds as novel hypoxia-inducible factor (HIF) -1 inhibitors. Bioorg Med Chem. 2015 Apr 15;23 (8) :1776-87.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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