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MSDC 0160 (Standard)

CAT: 0804-HY-100550RSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-100550RSize:1 Each
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Description
MSDC 0160 (Standard) is the analytical standard of MSDC 0160. This product is intended for research and analytical applications. MSDC 0160 (Mitoglitazone) is a mitochondrial target of thiazolidinediones (mTOT) -modulating insulin sensitizer and a modulator of mitochondrial pyruvate carrier (MPC). MSDC 0160 is a thiazolidinedione (TZD) with antidiabetic and neuroprotective activities. MSDC 0160 has the potential for Alzheimer′s disease[1][2].
CAS Number
146062-49-9
Target
Insulin Receptor; Mitochondrial Metabolism; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others; Protein Tyrosine Kinase/RTK
Field of Research
Neurological Disease; Endocrinology
Smiles
O=C(N1)SC(CC2=CC=C(OCC(C3=NC=C(CC)C=C3)=O)C=C2)C1=O
Molecular Formula
C19H18N2O4S
Molecular Weight
370.42
References & Citations
[1]Rohatgi N, et al. Novel insulin sensitizer modulates nutrient sensing pathways and maintains β-cell phenotype in human islets. PLoS One. 2013 May 1;8 (5) :e62012.|[2]Ghosh A, et al. Mitochondrial pyruvate carrier regulates autophagy, inflammation, and neurodegeneration inexperimental models of Parkinson's disease. Sci Transl Med. 2016 Dec 7;8 (368) :368ra174.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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