Thalidomide-pyrrolidine-C-azaspiro

• UNSPSC Description:

  Thalidomide-pyrrolidine-C-azaspiro is an E3 Ligase Ligand-Linker Conjugate. Thalidomide-pyrrolidine-C-azaspiro can be used to synthesize CW-3308 (HY-159579)[1].

• Target Antigen:

  E3 Ligase Ligand-Linker Conjugates

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  cancer

• Assay Protocol:

  https://www.medchemexpress.com/thalidomide-pyrrolidine-c-azaspiro.html

• Smiles:

  O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=C4C(CN(CC(CC5)CCC65CCNCC6)C4)=C3)=O

• Molecular Weight:

  464.56

• References & Citations:

  [1]Wang C, et al. Discovery of CW-3308 as a Potent, Selective, and Orally Efficacious PROTAC Degrader of BRD9. J Med Chem. 2024 Aug 22;67(16):14125-14154.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2832871-47-1