LY 245769

CAT: 0804-HY-123575Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-123575Size:1 Each
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Description
LY 245769, a omega-trifluoro analog, is a leukotriene E4 (LTE4) inhibitor. LY 245769 interfers the omega-oxidation of N-acetyl-LTE4 and leukotriene B4 (LTB4) with IC50s of 4 μM[1].
CAS Number
[127345-02-2]
UNSPSC
12352005
Target
Leukotriene Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ly-245769.html
Smiles
O[C@@H](C1=CC=CC(C2=NN=NN2)=C1)[C@@H](/C=C/C=C\CCCCCCCCC(F)(F)F)SCCC3=NN=NN3
Molecular Formula
C25H33F3N8OS
Molecular Weight
550.64
References & Citations
[1]G Jedlitschky, et al. Inhibition of leukotriene omega-oxidation by omega-trifluoro analogs of leukotrienes. Arch Biochem Biophys. 1990 Nov 1;282 (2) :333-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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