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Anti-APLP2 Polyclonal Antibody

CAT: 0793-39-2123-100Size: 100 µg/VialDry Ice: NoHazardous: No
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CAT#:0793-39-2123-100Size:100 µg/Vial
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
APLP2 (Amyloid beta (A4) precursor-like protein 2), also known as CDEBP or SPERM MEMBRANE PROTEIN, is a protein that in humans is encoded by the APLP2 gene. The APLP2 gene is mapped on 11q24.3. The human amyloid precursor-like protein APLP2 is a highly conserved homolog of a sequence-specific DNA-binding mouse protein with an important function in the cell cycle. APLP2 along with APLP1 are important modulators of glucose and insulin homeostasis. APLP2 associates with antigen presentation molecules like MHC class I molecules and regulates their surface expression by enhancing endocytosis.
Product Name Alternative
Amyloid-like protein 2; APLP-2; APPH; Amyloid protein homolog; CDEI box-binding protein; CDEBP; APLP2; APPL2
Gene Name
APLP2
Gene ID
334
UniProt
Q06481
Host
Rabbit
Reactivity
Human
Target Antigen
Amyloid-like protein 2 (APLP-2)
Clonality
Polyclonal
Applications
WB
Purification
Immunogen affinity purified.
Components
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitute : Add 0.2ml of distilled water will yield a concentration of 500ug/mL.
Storage Conditions
At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Applications Notes
Western blot : 0.1-0.5μg/ml; Immunohistochemistry (Paraffin-embedded Section) : 0.5-1μg/ml
Isotype
Rabbit IgG

UniProtKB · Q06481

Amyloid beta precursor like protein 2

APLP2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q06481
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
APLP2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B3KXX9, H7BXI4, Q13861, Q14594, Q14662, Q71U10, Q7M4L3, Q9BT36
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembraneNucleus

Ligand

CopperMetal-binding

PTM

Disulfide bondGlycoproteinPhosphoproteinProteoglycan

Molecular function

DNA-bindingProtease inhibitorSerine protease inhibitor

Domain

SignalTransmembraneTransmembrane helix

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