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APLP2 Polyclonal Antibody

CAT: 0965-JOT-AP00520-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP00520-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
APLP2 encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. Amyloid-like protein 2 is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
CAS Number
9007-83-4
Synonyms
APLP2; APPL2; Amyloid-like protein 2; APLP-2; APPH; Amyloid protein homolog; CDEI box-binding protein; CDEBP
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human APLP2. AA range:714-763
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
86956
Antibody Type
Primary antibody
Isotype
IgG

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