BAMB-4

• Description:

  BAMB-4 (ITPKA-IN-C14) is a specific and membrane-permeable ITPKA inhibitor. BAMB-4 has high stability and membrane permeability and against the inositol-1,4,5-trisphosphate (InsP3) kinase activity of inositol-1,4,5-trisphosphate-3-kinase A (ITPKA) with an IC50 value of 20 μM. BAMB-4 can be used for the research of metastasis of lung cancer[1].

• Product Name Alternative:

  ITPKA-IN-C14

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Phosphatase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/BAMB-4.html

• Purity:

  99.99

• Solubility:

  DMSO : ≥ 40 mg/mL

• Smiles:

  O=C (C1=CC=C (C) C=C1) NC2=NOC3=CC=CC=C23

• Molecular Formula:

  C15H12N2O2

• Molecular Weight:

  252.27

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Dominik Schröder, et al. Identification of a new membrane-permeable inhibitor against inositol-1,4,5-trisphosphate-3-kinase A. Biochem Biophys Res Commun

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  891025-25-5