p38 MAPK-IN-1
CAT:
804-HY-12839-05
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
p38 MAPK-IN-1
- CAS Number: 1006378-90-0
- UNSPSC Description: p38 MAPK-IN-1 (Compound 4) is a novel potent and selective inhibitor of p38 MAPK with IC50 of 68 nM. p38 MAPK-IN-1 shows sustained levels, low clearance and good bioavailability.
- Target Antigen: Autophagy; p38 MAPK
- Type: Reference compound
- Related Pathways: Autophagy;MAPK/ERK Pathway
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/p38-MAPK-IN-1.html
- Purity: 99.58
- Solubility: DMSO : 33.33 mg/mL (ultrasonic;warming;heat to 60°C)
- Smiles: FC1=CC(F)=C(C2=CC=NC(C2=CC=[NH+]3[O-])=C3C4=C(C)C=CC=C4)C=C1
- Molecular Weight: 349.35
- References & Citations: [1]Lumeras W, et al. 1,7-Naphthyridine 1-oxides as novel potent and selective inhibitors of p38 mitogen activated protein kinase. J Med Chem. 2011 Nov 24;54(22):7899-910.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported