HATU

• Description :

  HATU (1-[Bis (dimethylamino) methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium 3-oxid hexafluorophosphate) is a reagent used in peptide coupling chemistry to generate an active ester from a carboxylic acid. HATU can be used along with Hünig's base (N, N-diisopropylethylamine, DIPEA) to form amide bonds[1].

• UNSPSC :

  12352200

• Hazard Statement :

  H317, H334

• Target :

  Biochemical Assay Reagents

• Related Pathways :

  Others

• Field of Research :

  Others

• Purity :

  99.98

• Solubility :

  DMSO : 200 mg/mL (ultrasonic)

• Smiles :

  F[P-](F)(F)(F)(F)F.C/[N+](C)=C(N(C)C)/ON1C2=NC=CC=C2N=N1

• Molecular Formula :

  C10H15F6N6OP

• Molecular Weight :

  380.23

• Precautions :

  H317, H334

• References & Citations :

  [1]Louis A, et al. 1-Hydroxy-7-azabenzotriazole. An efficient peptide coupling additive. J. Am. Chem. Soc. 1993, 115, 10, 4397–4398

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Biochemical Assay Reagents

• Clinical Information :

  No Development Reported

• CAS Number :

  [148893-10-1]