(E) -JP-2-196 (TFA)

CAT: 0804-HY-W854844A-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-W854844A-01Size:5 mg
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Description
JP-2-196 (TFA) is a molecular glue handle that can bind to the E3-ubiquitin ligases (RNF126, LRSAM1, RNF40, MID2, and RNF14) in vitro. JP-2-196 (TFA) can be used to synthesize molecular glue degraders[1].
CAS Number
[3065021-33-9]
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Purity
97.89
Smiles
OC(C(F)(F)F)=O.O=C(N1CCNCC1)/C=C/C(C2=CC=C(C=C2)OC)=O
Molecular Formula
C17H19F3N2O5
Molecular Weight
388.34
References & Citations
[1]Toriki, E. S., et al., (2023) . Rational Chemical Design of Molecular Glue Degraders. ACS central science, 9 (5), 915–926.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature, keep dry and cool
Scientific Category
Reference compound2
Clinical Information
No Development Reported

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