(E) -JP-2-196 (TFA)

• Description :

  JP-2-196 (TFA) is a molecular glue handle that can bind to the E3-ubiquitin ligases (RNF126, LRSAM1, RNF40, MID2, and RNF14) in vitro. JP-2-196 (TFA) can be used to synthesize molecular glue degraders[1].

• UNSPSC :

  12352005

• Target :

  E3 Ligase Ligand-Linker Conjugates

• Related Pathways :

  PROTAC

• Field of Research :

  Cancer

• Purity :

  97.89

• Smiles :

  OC(C(F)(F)F)=O.O=C(N1CCNCC1)/C=C/C(C2=CC=C(C=C2)OC)=O

• Molecular Formula :

  C17H19F3N2O5

• Molecular Weight :

  388.34

• References & Citations :

  [1]Toriki, E. S., et al., (2023) . Rational Chemical Design of Molecular Glue Degraders. ACS central science, 9 (5), 915–926.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  Store at room temperature, keep dry and cool

• Scientific Category :

  Reference compound2

• Clinical Information :

  No Development Reported

• CAS Number :

  [3065021-33-9]