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Idebenone-13C, d3

CAT: 0804-HY-W777283-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-W777283-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Idebenone-13C, d3 is the deuterium labeled and 13C-labeled Idebenone (HY-N0303) . Idebenone, a well-appreciated mitochondrial protectant, exhibits protective efficacy against neurotoxicity and can be used for the research of Alzheimer's disease, Huntington's disease. Idebenone (oxidised form) has a dose-dependent inhibitory effect on the enzymatic metabolism of arachidonic acid in astroglial homogenates (IC50=16.65 μM) [1]. Idebenone, a coenzyme Q10 analog and an antioxidant, induces apoptotic cell death in the human dopaminergic neuroblastoma SHSY-5Y cells[2]. Idebenone quickly crosses the blood-brain barrier.
CAS Number
[1189907-75-2]
UNSPSC
12352211
Target
Apoptosis; Isotope-Labeled Compounds; Mitochondrial Metabolism
Related Pathways
Apoptosis; Metabolic Enzyme/Protease; Others
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Smiles
O=C(C(CCCCCCCCCCO)=C(C1=O)C)C(OC)=C1O[13C]([2H])([2H])[2H]
Molecular Formula
C18 13CH27D3O5
Molecular Weight
342.45
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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