Lupeol-d3

• Description:

  Lupeol-d3 is the deuterium labeled Lupeol (HY-N0790) . Lupeol is an active pentacyclic triterpenoid, has anti-oxidant, anti-mutagenic, anti-tumor and anti-inflammatory activity. Lupeol is a potent?androgen receptor? (AR) ?inhibitor and can be used for?cancer?research, especially prostate?cancer?of androgen-dependent phenotype (ADPC) and castration resistant phenotype (CRPC) [1].

• UNSPSC:

  12352211

• Target:

  Androgen Receptor; Apoptosis; Isotope-Labeled Compounds

• Related Pathways:

  Apoptosis; Others; Vitamin D Related/Nuclear Receptor

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Smiles:

  [H][C@]12CC[C@]3([C@@](C)(CC[C@]4(C(C)([C@]([2H])(C([2H])(C[C@@]43C)[2H])O)C)[H])[C@]1(C)CC[C@](C)([C@@]25[H])CC[C@H]5C(C)=C)[H]

• Molecular Formula:

  C30H47D3O

• Molecular Weight:

  429.74

• References & Citations:

  [1]Siddique HR, et al. Lupeol, a novel androgen receptor inhibitor: implications in prostate cancer therapy. Clin Cancer Res. 2011 Aug 15;17 (16) :5379-91.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported